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» Computing similarity between piecewise-linear functions
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BMCBI
2010
156views more  BMCBI 2010»
13 years 7 months ago
Comparative classification of species and the study of pathway evolution based on the alignment of metabolic pathways
Background: Pathways provide topical descriptions of cellular circuitry. Comparing analogous pathways reveals intricate insights into individual functional differences among speci...
Adi Mano, Tamir Tuller, Oded Béjà, R...
BMCBI
2006
120views more  BMCBI 2006»
13 years 7 months ago
Optimizing amino acid substitution matrices with a local alignment kernel
Background: Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, cal...
Hiroto Saigo, Jean-Philippe Vert, Tatsuya Akutsu
MMS
2010
13 years 5 months ago
Asynchronous reflections: theory and practice in the design of multimedia mirror systems
-- In this paper, we present a theoretical framing of the functions of a mirror by breaking the synchrony between the state of a reference object and its reflection. This framing p...
Wei Zhang, Bo Begole, Maurice Chu
JCC
2011
154views more  JCC 2011»
12 years 10 months ago
Can we trust docking results? Evaluation of seven commonly used programs on PDBbind database
: Docking is one of the most commonly used techniques in drug design. It is used for both identifying correct poses of a ligand in the binding site of a protein as well as for the ...
Dariusz Plewczynski, Michal Lazniewski, Rafal Augu...
BIBE
2005
IEEE
14 years 29 days ago
Selecting Informative Genes from Microarray Dataset by Incorporating Gene Ontology
Selecting informative genes from microarray experiments is one of the most important data analysis steps for deciphering biological information imbedded in such experiments. Howev...
Xian Xu, Aidong Zhang