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    BMCBI
    2010
    90views more  BMCBI 2010»
    Local alignment of generalized k-base encoded DNA sequence
    13 years 10 months ago
    Local alignment of generalized k-base encoded DNA sequence
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    Background: DNA sequence comparison is a well-studied problem, in which two DNA sequences are compared using a weighted edit distance. Recent DNA sequencing technologies however o...
    Nils Homer, Stanley F. Nelson, Barry Merriman
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    BMCBI
    2010
    112views more  BMCBI 2010»
    A boundary delimitation algorithm to approximate cell soma volumes of bipolar cells from topographical data obtained by scanning
    13 years 10 months ago
    A boundary delimitation algorithm to approximate cell soma volumes of bipolar cells from topographical data obtained by scanning
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    Background: Cell volume determination plays a pivotal role in the investigation of the biophysical mechanisms underlying various cellular processes. Whereas light microscopy in pr...
    Patrick Happel, Kerstin Moller, Ralf Kunz, Irmgard...
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    BMCBI
    2010
    131views more  BMCBI 2010»
    Prediction of epigenetically regulated genes in breast cancer cell lines
    13 years 10 months ago
    Prediction of epigenetically regulated genes in breast cancer cell lines
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    Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
    Leandro A. Loss, Anguraj Sadanandam, Steffen Durin...
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    BMCBI
    2010
    122views more  BMCBI 2010»
    An overview of the CellML API and its implementation
    13 years 10 months ago
    An overview of the CellML API and its implementation
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    Background: CellML is an XML based language for representing mathematical models, in a machine-independent form which is suitable for their exchange between different authors, and...
    Andrew K. Miller, Justin Marsh, Adam Reeve, Alan G...
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    BMCBI
    2010
    109views more  BMCBI 2010»
    Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model
    13 years 10 months ago
    Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model
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    Background: The binding of peptide fragments of extracellular peptides to class II MHC is a crucial event in the adaptive immune response. Each MHC allotype generally binds a dist...
    Andrew J. Bordner, Hans D. Mittelmann
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