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BMCBI
2010
2010
Towards the systematic discovery of signal transduction networks using phosphorylation dynamics data
13 years 8 months ago
Background: Phosphorylation is a ubiquitous and fundamental regulatory mechanism that controls signal transduction in living cells. The number of identified phosphoproteins and th...
BMCBI
2010
13 years 8 months ago
2010
Background: The construction of interaction networks between proteins is central to understanding the underlying biological processes. However, since many useful relations are exc...
BMCBI
2010
13 years 8 months ago
2010
Background: With the continuously increasing demands on knowledge- and data-management that databases have to meet, ontologies and the theories of granularity they use become more...
BMCBI
2010
13 years 8 months ago
2010
Background: Network Component Analysis (NCA) has been used to deduce the activities of transcription factors (TFs) from gene expression data and the TF-gene binding relationship. ...
BMCBI
2010
13 years 8 months ago
2010
Emerging knowledge of whole prokaryotic transcriptomes could validate a number of theoretical concepts introduced in the early days of genomics. What are the rules connecting gene...