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» Conservativity in Structured Ontologies
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BMCBI
2006
101views more  BMCBI 2006»
15 years 4 months ago
Hierarchical modularity of nested bow-ties in metabolic networks
Background: The exploration of the structural topology and the organizing principles of genomebased large-scale metabolic networks is essential for studying possible relations bet...
Jing Zhao, Hong Yu, Jianhua Luo, Zhi-Wei Cao, Yi-X...
BMCBI
2005
92views more  BMCBI 2005»
15 years 4 months ago
Predicting functional sites with an automated algorithm suitable for heterogeneous datasets
Background: In a previous report (La et al., Proteins, 2005), we have demonstrated that the identification of phylogenetic motifs, protein sequence fragments conserving the overal...
David La, Dennis R. Livesay
BMCBI
2005
115views more  BMCBI 2005»
15 years 4 months ago
Graphical representation of ribosomal RNA probe accessibility data using ARB software package
Background: Taxon specific hybridization probes in combination with a variety of commonly used hybridization formats nowadays are standard tools in microbial identification. A fre...
Yadhu Kumar, Ralf Westram, Sebastian Behrens, Bern...
BMCBI
2005
114views more  BMCBI 2005»
15 years 4 months ago
A new decoding algorithm for hidden Markov models improves the prediction of the topology of all-beta membrane proteins
Background: Structure prediction of membrane proteins is still a challenging computational problem. Hidden Markov models (HMM) have been successfully applied to the problem of pre...
Piero Fariselli, Pier Luigi Martelli, Rita Casadio
BMCBI
2010
131views more  BMCBI 2010»
14 years 11 months ago
Dynamics based alignment of proteins: an alternative approach to quantify dynamic similarity
Background: The dynamic motions of many proteins are central to their function. It therefore follows that the dynamic requirements of a protein are evolutionary constrained. In or...
Márton Münz, Rune B. Lyngsø, Jo...