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» Constraint Based Methods for Biological Sequence Analysis
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BMCBI
2005
103views more  BMCBI 2005»
15 years 4 months ago
Quadratic regression analysis for gene discovery and pattern recognition for non-cyclic short time-course microarray experiments
Background: Cluster analyses are used to analyze microarray time-course data for gene discovery and pattern recognition. However, in general, these methods do not take advantage o...
Hua Liu, Sergey Tarima, Aaron S. Borders, Thomas V...
BMCBI
2010
99views more  BMCBI 2010»
15 years 4 months ago
Different effects of the probe summarization algorithms PLIER and RMA on high-level analysis of Affymetrix exon arrays
Background: Alternative splicing is an important mechanism that increases protein diversity and functionality in higher eukaryotes. Affymetrix exon arrays are a commercialized pla...
Yi Qu, Fei He, Yuchen Chen
BMCBI
2008
128views more  BMCBI 2008»
15 years 4 months ago
Validation of an NSP-based (negative selection pattern) gene family identification strategy
Background: Gene family identification from ESTs can be a valuable resource for analysis of genome evolution but presents unique challenges in organisms for which the entire genom...
Ronald L. Frank, Cyriac Kandoth, Fikret Erç...
BMCBI
2010
170views more  BMCBI 2010»
15 years 4 months ago
Analysis of lifestyle and metabolic predictors of visceral obesity with Bayesian Networks
Background: The aim of this study was to provide a framework for the analysis of visceral obesity and its determinants in women, where complex inter-relationships are observed amo...
Alex Aussem, André Tchernof, Sergio Rodrigu...
KDD
2009
ACM
178views Data Mining» more  KDD 2009»
16 years 4 months ago
Constrained optimization for validation-guided conditional random field learning
Conditional random fields(CRFs) are a class of undirected graphical models which have been widely used for classifying and labeling sequence data. The training of CRFs is typicall...
Minmin Chen, Yixin Chen, Michael R. Brent, Aaron E...