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» Constraint Based Methods for Biological Sequence Analysis
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BIODATAMINING
2008
96views more  BIODATAMINING 2008»
15 years 4 months ago
Fast approximate hierarchical clustering using similarity heuristics
Background: Agglomerative hierarchical clustering (AHC) is a common unsupervised data analysis technique used in several biological applications. Standard AHC methods require that...
Meelis Kull, Jaak Vilo
ISMB
1993
15 years 5 months ago
Knowledge Discovery in GENBANK
Wedescribe various methods designed to discover knowledge in the GenBanknucleic acid sequence database. Using a grammatical model of gene structure, we create a parse tree of a ge...
Jeffery S. Aaronson, Juergen Haas, G. Christian Ov...
BMCBI
2010
218views more  BMCBI 2010»
15 years 4 months ago
Fast multi-core based multimodal registration of 2D cross-sections and 3D datasets
Background: Solving bioinformatics tasks often requires extensive computational power. Recent trends in processor architecture combine multiple cores into a single chip to improve...
Michael Scharfe, Rainer Pielot, Falk Schreiber
BMCBI
2010
113views more  BMCBI 2010»
15 years 4 months ago
Probabilistic Principal Component Analysis for Metabolomic Data
Background: Data from metabolomic studies are typically complex and high-dimensional. Principal component analysis (PCA) is currently the most widely used statistical technique fo...
Gift Nyamundanda, Lorraine Brennan, Isobel Claire ...
BMCBI
2008
156views more  BMCBI 2008»
15 years 4 months ago
The unique probe selector: a comprehensive web service for probe design and oligonucleotide arrays
Background: Nucleic acid hybridization, a fundamental technique in molecular biology, can be modified into very effective and sensitive methods for detecting particular targets mi...
Shu-Hwa Chen, Chen-Zen Lo, Ming-Chi Tsai, Chao A. ...