1813 search results - page 7 / 363 » Constraint Based Methods for Biological Sequence Analysis |
ISMB
2001
13 years 8 months ago
2001
Accurately estimating probabilities from observations is important for probabilistic-based approaches to problems in computational biology. In this paper we present a biologically...
ALMOB
2006
13 years 7 months ago
2006
Background: Automated software tools for multiple alignment often fail to produce biologically meaningful results. In such situations, expert knowledge can help to improve the qua...
RECOMB
2003
Springer
14 years 7 months ago
2003
Springer
We propose a framework for modeling sequence motifs based on the maximum entropy principle (MEP). We recommend approximating short sequence motif distributions with the maximum en...
ISMB
1998
13 years 8 months ago
1998
A novel method to model and predict the location and orientation of alpha helices in membrane- spanning proteins is presented. It is based on a hidden Markov model (HMM) with an a...
BIOCOMP
2009
13 years 5 months ago
2009
- Identification and annotation of all the functional elements in the genome, including genes and regulatory sequences, is a fundamental challenge in genomics and computational bio...