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» Constraint Based Methods for Biological Sequence Analysis
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138
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BMCBI
2010
142views more  BMCBI 2010»
15 years 1 months ago
Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis
Background: High-throughput profiling of DNA methylation status of CpG islands is crucial to understand the epigenetic regulation of genes. The microarray-based Infinium methylati...
Pan Du, Xiao Zhang, Chiang-Ching Huang, Nadereh Ja...
146
Voted
BMCBI
2010
136views more  BMCBI 2010»
15 years 3 months ago
SCPS: a fast implementation of a spectral method for detecting protein families on a genome-wide scale
Background: An important problem in genomics is the automatic inference of groups of homologous proteins from pairwise sequence similarities. Several approaches have been proposed...
Tamás Nepusz, Rajkumar Sasidharan, Alberto ...
162
Voted
SIGMOD
2004
ACM
154views Database» more  SIGMOD 2004»
16 years 3 months ago
Computing Clusters of Correlation Connected Objects
The detection of correlations between different features in a set of feature vectors is a very important data mining task because correlation indicates a dependency between the fe...
Christian Böhm, Karin Kailing, Peer Krög...
BMCBI
2008
142views more  BMCBI 2008»
15 years 3 months ago
Strategies for measuring evolutionary conservation of RNA secondary structures
Background: Evolutionary conservation of RNA secondary structure is a typical feature of many functional non-coding RNAs. Since almost all of the available methods used for predic...
Andreas R. Gruber, Stephan H. F. Bernhart, Ivo L. ...
136
Voted
BMCBI
2005
97views more  BMCBI 2005»
15 years 3 months ago
Sequence variation in ligand binding sites in proteins
Background: The recent explosion in the availability of complete genome sequences has led to the cataloging of tens of thousands of new proteins and putative proteins. Many of the...
Thomas J. Magliery, Lynne Regan