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BMCBI
2008
152views more  BMCBI 2008»
13 years 7 months ago
Predicting biological system objectives de novo from internal state measurements
Background: Optimization theory has been applied to complex biological systems to interrogate network properties and develop and refine metabolic engineering strategies. For examp...
Erwin P. Gianchandani, Matthew A. Oberhardt, Antho...
BMCBI
2008
142views more  BMCBI 2008»
13 years 7 months ago
Strategies for measuring evolutionary conservation of RNA secondary structures
Background: Evolutionary conservation of RNA secondary structure is a typical feature of many functional non-coding RNAs. Since almost all of the available methods used for predic...
Andreas R. Gruber, Stephan H. F. Bernhart, Ivo L. ...
BMCBI
2008
114views more  BMCBI 2008»
13 years 7 months ago
WSPMaker: a web tool for calculating selection pressure in proteins and domains using window-sliding
Background: In the study of adaptive evolution, it is important to detect the protein coding sites where natural selection is acting. In general, the ratio of the rate of non-syno...
Yong Seok Lee, Tae-Hyung Kim, Tae-Wook Kang, Won-H...
COMGEO
2008
ACM
13 years 7 months ago
Optimal location of transportation devices
We consider algorithms for finding the optimal location of a simple transportation device, that we call a moving walkway, consisting of a pair of points in the plane between which ...
Jean Cardinal, Sébastien Collette, Ferran H...
CORR
2008
Springer
118views Education» more  CORR 2008»
13 years 7 months ago
Distributed Constrained Optimization with Semicoordinate Transformations
Recent work has shown how information theory extends conventional full-rationality game theory to allow bounded rational agents. The associated mathematical framework can be used ...
William G. Macready, David Wolpert