Background: Frameshift mutations in protein-coding DNA sequences produce a drastic change in the resulting protein sequence, which prevents classic protein alignment methods from ...
This paper complements McCarthy's "The well designed child", in part by putting it in a broader context, the space of possible well designed progeny, and in part by...
The threat of commoditization poses a real challenge for service providers. While the end-to-end principle is often paraphrased as “dumb network, smart end-systems”, the origi...
Background: It has repeatedly been shown that interacting protein families tend to have similar phylogenetic trees. These similarities can be used to predicting the mapping betwee...
Natural networks such as those between humans observed through their interactions or biological networks predicted based on various experimental measurements contain a wealth of i...