The rapid advances of genome-scale sequencing have brought out the necessity of developing new data processing techniques for enormous genomic data. Microarrays, for example, can g...
Background: Studies of differential expression that use Affymetrix GeneChip arrays are often carried out with a limited number of replicates. Reasons for this include financial co...
Motivation: Sigma factors regulate the expression of genes in Bacillus subtilis at the transcriptional level. First we assess the ability of currently available gene regulatory ne...
Michiel J. L. de Hoon, Yuko Makita, Seiya Imoto, K...
Abstract. This paper illustrates how the Quadratic Assignment Problem (QAP) is used as a mathematical model that helps to produce a visualization of microarray data, based on the r...
Mario Inostroza-Ponta, Alexandre Mendes, Regina Be...
Identifying gene regulatory networks from high-throughput gene expression data is one of the most important goals of bioinformatics, but it remains difficult to define what makes a...