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» Contextual alignment of biological sequences
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BMCBI
2005
115views more  BMCBI 2005»
13 years 7 months ago
Statistical distributions of optimal global alignment scores of random protein sequences
Background: The inference of homology from statistically significant sequence similarity is a central issue in sequence alignments. So far the statistical distribution function un...
Hongxia Pang, Jiaowei Tang, Su-Shing Chen, Shiheng...
IJCAI
2003
13 years 9 months ago
Comparing Best-First Search and Dynamic Programming for Optimal Multiple Sequence Alignment
Sequence alignment is an important problem in computational biology. We compare two different approaches to the problem of optimally aligning two or more character strings: bounde...
Heath Hohwald, Ignacio Thayer, Richard E. Korf
IPPS
2006
IEEE
14 years 1 months ago
Parallel multiple sequence alignment with local phylogeny search by simulated annealing
The problem of multiple sequence alignment is one of the most important problems in computational biology. In this paper we present a new method that simultaneously performs multi...
Jaroslaw Zola, Denis Trystram, Andrei Tchernykh, C...
BMCBI
2008
109views more  BMCBI 2008»
13 years 7 months ago
The meaning of alignment: lessons from structural diversity
Background: Protein structural alignment provides a fundamental basis for deriving principles of functional and evolutionary relationships. It is routinely used for structural cla...
Walter Pirovano, K. Anton Feenstra, Jaap Heringa
DILS
2005
Springer
14 years 1 months ago
Support for BioIndexing in BLASTgres
The ability to perform genome-wide and cross-genome data analyses can dramatically reduce the time required for new biological discoveries. This raises important issues in bioinfor...
Ruey-Lung Hsiao, Douglas Stott Parker Jr., Hung-ch...