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» Contextual alignment of biological sequences
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BMCBI
2004
125views more  BMCBI 2004»
13 years 7 months ago
A functional hierarchical organization of the protein sequence space
Background: It is a major challenge of computational biology to provide a comprehensive functional classification of all known proteins. Most existing methods seek recurrent patte...
Noam Kaplan, Moriah Friedlich, Menachem Fromer, Mi...
SC
2003
ACM
14 years 28 days ago
A Million-Fold Speed Improvement in Genomic Repeats Detection
This paper presents a novel, parallel algorithm for generating top alignments. Top alignments are used for finding internal repeats in biological sequences like proteins and gene...
John W. Romein, Jaap Heringa, Henri E. Bal
BMCBI
2006
129views more  BMCBI 2006»
13 years 7 months ago
EGenBio: A Data Management System for Evolutionary Genomics and Biodiversity
Background: Evolutionary genomics requires management and filtering of large numbers of diverse genomic sequences for accurate analysis and inference on evolutionary processes of ...
Laila A. Nahum, Matthew T. Reynolds, Zhengyuan O. ...
BMCBI
2011
12 years 11 months ago
Faster Smith-Waterman database searches with inter-sequence SIMD parallelisation
Background: The Smith-Waterman algorithm for local sequence alignment is more sensitive than heuristic methods for database searching, but also more time-consuming. The fastest ap...
Torbjørn Rognes
CIBCB
2006
IEEE
14 years 1 months ago
Prediction of the Number of Helices for the Twilight Zone Proteins
– Protein structure prediction is one of the core research areas in bioinformatics. This paper addresses the protein secondary structure prediction problem for the twilight zone ...
Kanaka Durga Kedarisetti, Ke Chen, Aashima Kapoor,...