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» Contextual alignment of biological sequences
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ISMB
1997
13 years 9 months ago
Standardized Representations of the Literature: Combining Diverse Sources of Ribosomal Data
We are building a knowledge base (KB) of published structural data on the 30s ribosomal subunit in prokaryotes. Our KB is distinguished by a standardized representation of biologi...
Russ B. Altman, Neil F. Abernethy, Richard O. Chen
BMCBI
2005
119views more  BMCBI 2005»
13 years 7 months ago
The distance-profile representation and its application to detection of distantly related protein families
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
Chin-Jen Ku, Golan Yona
ENGL
2008
78views more  ENGL 2008»
13 years 7 months ago
Threshold for Positional Weight Matrix
In biological sequence research, the positional weight matrix (PWM) is often used to search for putative transcription factor binding sites. A set of experimentally verified oligon...
Yunlian Pan, Sieu Phan
BMCBI
2006
107views more  BMCBI 2006»
13 years 7 months ago
A reinforced merging methodology for mapping unique peptide motifs in members of protein families
Background: Members of a protein family often have highly conserved sequences; most of these sequences carry identical biological functions and possess similar three-dimensional (...
Hao-Teng Chang, Tun-Wen Pai, Tan-Chi Fan, Bo-Han S...
JCB
2007
94views more  JCB 2007»
13 years 7 months ago
A Quantile Method for Sizing Optical Maps
Optical mapping is an integrated system for the analysis of single DNA molecules. It constructs restriction maps (noted as “optical map”) from individual DNA molecules present...
Haifeng Li, Anton Valouev, David C. Schwartz, Mich...