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    » Convergent algorithms for protein structural alignment
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    BMCBI
    2005
    119views more  BMCBI 2005»
    The distance-profile representation and its application to detection of distantly related protein families
    13 years 7 months ago
    The distance-profile representation and its application to detection of distantly related protein families
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    Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
    Chin-Jen Ku, Golan Yona
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    BMCBI
    2005
    198views more  BMCBI 2005»
    Clustering protein sequences with a novel metric transformed from sequence similarity scores and sequence alignments with neural
    13 years 7 months ago
    Clustering protein sequences with a novel metric transformed from sequence similarity scores and sequence alignments with neural
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    Background: The sequencing of the human genome has enabled us to access a comprehensive list of genes (both experimental and predicted) for further analysis. While a majority of t...
    Qicheng Ma, Gung-Wei Chirn, Richard Cai, Joseph D....
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    BMCBI
    2004
    208views more  BMCBI 2004»
    Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
    13 years 7 months ago
    Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
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    Background: Hidden Markov Models (HMMs) have proven very useful in computational biology for such applications as sequence pattern matching, gene-finding, and structure prediction...
    Vadim Alexandrov, Mark Gerstein
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    BIBE
    2007
    IEEE
    128views Bioinformatics» more  BIBE 2007»
    QOMA2: Optimizing the alignment of many sequences
    14 years 2 months ago
    QOMA2: Optimizing the alignment of many sequences
    Download  www.cise.ufl.edu
    Abstract—We consider the problem of aligning multiple protein sequences with the goal of maximizing the SP (Sum-of-Pairs) score, when the number of sequences is large. The QOMA (...
    Xu Zhang, Tamer Kahveci
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    BMCBI
    2005
    115views more  BMCBI 2005»
    Statistical distributions of optimal global alignment scores of random protein sequences
    13 years 7 months ago
    Statistical distributions of optimal global alignment scores of random protein sequences
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    Background: The inference of homology from statistically significant sequence similarity is a central issue in sequence alignments. So far the statistical distribution function un...
    Hongxia Pang, Jiaowei Tang, Su-Shing Chen, Shiheng...
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