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HOTOS
1999
IEEE
14 years 27 days ago
The Case for Efficient File Access Pattern Modeling
Most modern I/O systems treat each file access independently. However, events in a computer system are driven by programs. Thus, accesses to files occur in consistent patterns and...
Tom M. Kroeger, Darrell D. E. Long
FAST
2007
13 years 10 months ago
Disk Failures in the Real World: What Does an MTTF of 1, 000, 000 Hours Mean to You?
Component failure in large-scale IT installations is becoming an ever larger problem as the number of components in a single cluster approaches a million. In this paper, we presen...
Bianca Schroeder, Garth A. Gibson
MASCOTS
2008
13 years 10 months ago
Tackling the Memory Balancing Problem for Large-Scale Network Simulation
A key obstacle to large-scale network simulation over PC clusters is the memory balancing problem where a memory-overloaded machine can slow down an entire simulation due to disk ...
Hyojeong Kim, Kihong Park
BMCBI
2008
133views more  BMCBI 2008»
13 years 8 months ago
ElliPro: a new structure-based tool for the prediction of antibody epitopes
Background: Reliable prediction of antibody, or B-cell, epitopes remains challenging yet highly desirable for the design of vaccines and immunodiagnostics. A correlation between a...
Julia V. Ponomarenko, Huynh-Hoa Bui, Wei Li, Nicho...
BMCBI
2010
178views more  BMCBI 2010»
13 years 8 months ago
An improved method for scoring protein-protein interactions using semantic similarity within the Gene Ontology
Background: Semantic similarity measures are useful to assess the physiological relevance of protein-protein interactions (PPIs). They quantify similarity between proteins based o...
Shobhit Jain, Gary D. Bader