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BMCBI
2005
122views more  BMCBI 2005»
13 years 8 months ago
Quantitative analysis of EGR proteins binding to DNA: assessing additivity in both the binding site and the protein
Background: Recognition codes for protein-DNA interactions typically assume that the interacting positions contribute additively to the binding energy. While this is known to not ...
Jiajian Liu, Gary D. Stormo
CORR
2004
Springer
103views Education» more  CORR 2004»
13 years 8 months ago
Online convex optimization in the bandit setting: gradient descent without a gradient
We study a general online convex optimization problem. We have a convex set S and an unknown sequence of cost functions c1, c2, . . . , and in each period, we choose a feasible po...
Abraham Flaxman, Adam Tauman Kalai, H. Brendan McM...
BC
1998
96views more  BC 1998»
13 years 8 months ago
Evidence of phase transitions in heart period dynamics
Complexity measures of non-linear dynamics are a useful tool for quantifying observed stretching, folding, scaling and mixing processes in the Takens-reconstructed state space of h...
Henrik Bettermann, Peter Van Leeuwen
CIKM
2010
Springer
13 years 7 months ago
Fast and accurate estimation of shortest paths in large graphs
Computing shortest paths between two given nodes is a fundamental operation over graphs, but known to be nontrivial over large disk-resident instances of graph data. While a numbe...
Andrey Gubichev, Srikanta J. Bedathur, Stephan Seu...
ALGORITHMICA
2011
13 years 2 days ago
Algorithms for Marketing-Mix Optimization
Algorithms for determining quality/cost/price tradeoffs in saturated markets are consid-3 ered. A product is modeled by d real-valued qualities whose sum determines the unit cost ...
Joachim Gudmundsson, Pat Morin, Michiel H. M. Smid