Background: Statistical methods for ranking differentially expressed genes (DEGs) from gene expression data should be evaluated with regard to high sensitivity, specificity, and r...
This paper presents a novel method integrating gene-gene interaction information and Gene Ontology for the construction of new gene sets that are potentially enriched. Enrichment o...
Background: The detection of small yet statistically significant differences in gene expression in spotted DNA microarray studies is an ongoing challenge. Meeting this challenge r...
Background: It is common for the results of a microarray study to be analyzed in the context of biologically-motivated groups of genes such as pathways or Gene Ontology categories...
Homin K. Lee, William Braynen, Kiran Keshav, Paul ...
Currently, the cDNA and genomic sequence projects are processing at such a rapid rate that more and more gene data become available. New methods are needed to efficiently and eff...