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» Cross-Platform Analysis with Binarized Gene Expression Data
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BMCBI
2008
82views more  BMCBI 2008»
15 years 6 months ago
Gene expression profile of peripheral blood mononuclear cells in response to HIV-VLPs stimulation
Background: Baculovirus-expressed HIV-1 Pr55gag Virus-Like Particles (HIV-VLPs) induce maturation and activation of monocyte-derived dendritic cells (MDDCs) with a production of T...
Luigi Buonaguro, Alessandro Monaco, Eleonora Aric&...
BMCBI
2006
119views more  BMCBI 2006»
15 years 6 months ago
LS-NMF: A modified non-negative matrix factorization algorithm utilizing uncertainty estimates
Background: Non-negative matrix factorisation (NMF), a machine learning algorithm, has been applied to the analysis of microarray data. A key feature of NMF is the ability to iden...
Guoli Wang, Andrew V. Kossenkov, Michael F. Ochs
BMCBI
2006
120views more  BMCBI 2006»
15 years 6 months ago
A factor analysis model for functional genomics
Background: Expression array data are used to predict biological functions of uncharacterized genes by comparing their expression profiles to those of characterized genes. While b...
Rafal Kustra, Romy Shioda, Mu Zhu
BMCBI
2005
113views more  BMCBI 2005»
15 years 5 months ago
Normal uniform mixture differential gene expression detection for cDNA microarrays
Background: One of the primary tasks in analysing gene expression data is finding genes that are differentially expressed in different samples. Multiple testing issues due to the ...
Nema Dean, Adrian E. Raftery
248
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AINA
2008
IEEE
16 years 11 days ago
Missing Value Estimation for Time Series Microarray Data Using Linear Dynamical Systems Modeling
The analysis of gene expression time series obtained from microarray experiments can be effectively exploited to understand a wide range of biological phenomena from the homeostat...
Connie Phong, Raul Singh