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    BMCBI
    2007
    103views more  BMCBI 2007»
    Dynamic simulation of regulatory networks using SQUAD
    13 years 9 months ago
    Dynamic simulation of regulatory networks using SQUAD
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    Background: The ambition of most molecular biologists is the understanding of the intricate network of molecular interactions that control biological systems. As scientists uncove...
    Alessandro Di Cara, Abhishek Garg, Giovanni De Mic...
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    BMCBI
    2008
    126views more  BMCBI 2008»
    c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
    13 years 9 months ago
    c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
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    Background: Computational methods for characterizing novel transcription factor binding sites search for sequence patterns or "motifs" that appear repeatedly in genomic ...
    Katerina Kechris, Hao Li
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    BMCBI
    2006
    145views more  BMCBI 2006»
    GEM System: automatic prototyping of cell-wide metabolic pathway models from genomes
    13 years 9 months ago
    GEM System: automatic prototyping of cell-wide metabolic pathway models from genomes
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    Background: Successful realization of a "systems biology" approach to analyzing cells is a grand challenge for our understanding of life. However, current modeling appro...
    Kazuharu Arakawa, Yohei Yamada, Kosaku Shinoda, Yo...
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    BMCBI
    2006
    108views more  BMCBI 2006»
    Probe set algorithms: is there a rational best bet?
    13 years 9 months ago
    Probe set algorithms: is there a rational best bet?
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    Affymetrix microarrays have become a standard experimental platform for studies of mRNA expression profiling. Their success is due, in part, to the multiple oligonucleotide featur...
    Jinwook Seo, Eric P. Hoffman
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    BMCBI
    2006
    129views more  BMCBI 2006»
    A literature-based similarity metric for biological processes
    13 years 9 months ago
    A literature-based similarity metric for biological processes
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    Background: Recent analyses in systems biology pursue the discovery of functional modules within the cell. Recognition of such modules requires the integrative analysis of genome-...
    Monica Chagoyen, Pedro Carmona-Saez, Concha Gil, J...
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