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BMCBI
2005
80views more  BMCBI 2005»
13 years 7 months ago
Gene finding in the chicken genome
Background: Despite the continuous production of genome sequence for a number of organisms, reliable, comprehensive, and cost effective gene prediction remains problematic. This i...
Eduardo Eyras, Alexandre Reymond, Robert Castelo, ...
BMCBI
2005
104views more  BMCBI 2005»
13 years 7 months ago
Scoring functions for transcription factor binding site prediction
Background: Transcription factor binding site (TFBS) prediction is a difficult problem, which requires a good scoring function to discriminate between real binding sites and backg...
Markus T. Friberg, Peter von Rohr, Gaston H. Gonne...
BMCBI
2005
103views more  BMCBI 2005»
13 years 7 months ago
Many accurate small-discriminatory feature subsets exist in microarray transcript data: biomarker discovery
Background: Molecular profiling generates abundance measurements for thousands of gene transcripts in biological samples such as normal and tumor tissues (data points). Given such...
Leslie Grate
BMCBI
2005
107views more  BMCBI 2005»
13 years 7 months ago
A stepwise framework for the normalization of array CGH data
Background: In two-channel competitive genomic hybridization microarray experiments, the ratio of the two fluorescent signal intensities at each spot on the microarray is commonly...
Mehrnoush Khojasteh, Wan L. Lam, Rabab Kreidieh Wa...
BMCBI
2005
169views more  BMCBI 2005»
13 years 7 months ago
MAPPER: a search engine for the computational identification of putative transcription factor binding sites in multiple genomes
Background: Cis-regulatory modules are combinations of regulatory elements occurring in close proximity to each other that control the spatial and temporal expression of genes. Th...
Voichita D. Marinescu, Isaac S. Kohane, Alberto Ri...