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» Current approaches to gene regulatory network modelling
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TCBB
2008
116views more  TCBB 2008»
13 years 8 months ago
Inferring Connectivity of Genetic Regulatory Networks Using Information-Theoretic Criteria
Recently, the concept of mutual information has been proposed for inferring the structure of genetic regulatory networks from gene expression profiling. After analyzing the limitat...
Wentao Zhao, Erchin Serpedin, Edward R. Dougherty
IDA
2008
Springer
13 years 8 months ago
ExpertDiscovery system application for the hierarchical analysis of eukaryotic transcription regulatory regions based on DNA cod
We developed Relational Data Mining approach which allows to overcome essential limitations of the Data Mining and Knowledge Discovery techniques. In the paper the approach was im...
I. V. Khomicheva, Eugenii E. Vityaev, Elena A. Ana...
JMLR
2006
103views more  JMLR 2006»
13 years 8 months ago
MinReg: A Scalable Algorithm for Learning Parsimonious Regulatory Networks in Yeast and Mammals
In recent years, there has been a growing interest in applying Bayesian networks and their extensions to reconstruct regulatory networks from gene expression data. Since the gene ...
Dana Pe'er, Amos Tanay, Aviv Regev
TCBB
2011
13 years 3 months ago
Learning Genetic Regulatory Network Connectivity from Time Series Data
Recent experimental advances facilitate the collection of time series data that indicate which genes in a cell are expressed. This paper proposes an efficient method to generate th...
Nathan A. Barker, Chris J. Myers, Hiroyuki Kuwahar...
BIOINFORMATICS
2006
118views more  BIOINFORMATICS 2006»
13 years 8 months ago
A probabilistic dynamical model for quantitative inference of the regulatory mechanism of transcription
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Magnus Rattray, Neil D. Lawrenc...