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» Current approaches to gene regulatory network modelling
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TCBB
2010
89views more  TCBB 2010»
13 years 6 months ago
Model Composition for Macromolecular Regulatory Networks
—Models of regulatory networks become more difficult to construct and understand as they grow in size and complexity. Large models are usually built up from smaller models, repre...
Ranjit Randhawa, Clifford A. Shaffer, John J. Tyso...
BMCBI
2006
181views more  BMCBI 2006»
13 years 8 months ago
The comprehensive updated regulatory network of Escherichia coli K-12
Background: Escherichia coli is the model organism for which our knowledge of its regulatory network is the most extensive. Over the last few years, our project has been collectin...
Heladia Salgado, Alberto Santos-Zavaleta, Socorro ...
CSB
2003
IEEE
124views Bioinformatics» more  CSB 2003»
14 years 1 months ago
SMASHing regulatory sites in DNA by human
Regulatory sequence elements provide important clues to understanding and predicting gene expression. Although the binding sites for hundreds of transcription factors are known, t...
Mihaela Zavolan, Nicholas D. Socci, Nikolaus Rajew...
BMCBI
2004
115views more  BMCBI 2004»
13 years 8 months ago
Quantifying the relationship between co-expression, co-regulation and gene function
Background: It is thought that genes with similar patterns of mRNA expression and genes with similar functions are likely to be regulated via the same mechanisms. It has been diff...
Dominic J. Allocco, Isaac S. Kohane, Atul J. Butte
TACAS
2007
Springer
92views Algorithms» more  TACAS 2007»
14 years 2 months ago
Model Checking Liveness Properties of Genetic Regulatory Networks
Abstract. Recent studies have demonstrated the possibility to build genetic regulatory networks that confer a desired behavior to a living organism. However, the design of these ne...
Grégory Batt, Calin Belta, Ron Weiss