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» DIG - a system for gene annotation and functional discovery
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BMCBI
2010
178views more  BMCBI 2010»
13 years 7 months ago
An improved method for scoring protein-protein interactions using semantic similarity within the Gene Ontology
Background: Semantic similarity measures are useful to assess the physiological relevance of protein-protein interactions (PPIs). They quantify similarity between proteins based o...
Shobhit Jain, Gary D. Bader
BIOCOMP
2008
13 years 8 months ago
Reverse Engineering Module Networks by PSO-RNN Hybrid Modeling
Background: Inferring a gene regulatory network (GRN) from high throughput biological data is often an under-determined problem and is a challenging task due to the following reas...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
BMCBI
2005
96views more  BMCBI 2005»
13 years 7 months ago
Overview of BioCreAtIvE task 1B: normalized gene lists
Background: Our goal in BioCreAtIve has been to assess the state of the art in text mining, with emphasis on applications that reflect real biological applications, e.g., the cura...
Lynette Hirschman, Marc E. Colosimo, Alexander A. ...
BIBE
2005
IEEE
14 years 1 months ago
Selecting Informative Genes from Microarray Dataset by Incorporating Gene Ontology
Selecting informative genes from microarray experiments is one of the most important data analysis steps for deciphering biological information imbedded in such experiments. Howev...
Xian Xu, Aidong Zhang
BMCBI
2006
127views more  BMCBI 2006»
13 years 7 months ago
Using local gene expression similarities to discover regulatory binding site modules
Background: We present an approach designed to identify gene regulation patterns using sequence and expression data collected for Saccharomyces cerevisae. Our main goal is to rela...
Bartek Wilczynski, Torgeir R. Hvidsten, Andriy Kry...