We discuss the problem of optimally "finishing" a partially sequenced, reconstructed DNA segment. At first sight, this appears to be computationally hard. We construct a...
Background: Second generation sequencing technologies yield DNA sequence data at ultra high-throughput. Common to most biological applications is a mapping of the reads to an almo...
Manuel Holtgrewe, Anne-Katrin Emde, David Weese, K...
Whiplash PCR (WPCR), due to Hagiya et al. [1], is a novel technique for autonomous molecular computation where a state machine is implemented with a single stranded DNA molecule a...
A very basic problem in all DNA computations is finding a good encoding. Apart from the fact that they must provide a solution, the strands involved should not exhibit any undesir...