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CANDC
2008
ACM
13 years 7 months ago
'Genome order index' should not be used for defining compositional constraints in nucleotide sequences
Background: The Z-curve is a three dimensional representation of DNA sequences proposed over a decade ago and has been extensively applied to sequence segmentation, horizontal gen...
Eran Elhaik, Dan Graur, Kresimir Josic
CGF
2008
142views more  CGF 2008»
13 years 7 months ago
Visualizing Genome Expression and Regulatory Network Dynamics in Genomic and Metabolic Context
DNA microarrays are used to measure the expression levels of thousands of genes simultaneously. In a time series experiment, the gene expressions are measured as a function of tim...
Michel A. Westenberg, Sacha A. F. T. van Hijum, Os...
ALMOB
2006
106views more  ALMOB 2006»
13 years 7 months ago
Multiple sequence alignment with user-defined anchor points
Background: Automated software tools for multiple alignment often fail to produce biologically meaningful results. In such situations, expert knowledge can help to improve the qua...
Burkhard Morgenstern, Sonja J. Prohaska, Dirk P&ou...
BMCBI
2006
112views more  BMCBI 2006»
13 years 7 months ago
GENOMEMASKER package for designing unique genomic PCR primers
Background: The design of oligonucleotides and PCR primers for studying large genomes is complicated by the redundancy of sequences. The eukaryotic genomes are particularly diffic...
Reidar Andreson, Eric Reppo, Lauris Kaplinski, Mai...
BMCBI
2006
100views more  BMCBI 2006»
13 years 7 months ago
DNPTrapper: an assembly editing tool for finishing and analysis of complex repeat regions
Background: Many genome projects are left unfinished due to complex, repeated regions. Finishing is the most time consuming step in sequencing and current finishing tools are not ...
Erik Arner, Martti T. Tammi, Anh-Nhi Tran, Ellen K...