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ISMB
2000
13 years 11 months ago
A Statistical Method for Finding Transcription Factor Binding Sites
Understanding the mechanismsthat determine the regulation of geneexpression is an important and challenging problem. A fundamental subproblem is to identify DNA-bindingsites for u...
Saurabh Sinha, Martin Tompa
ISMB
1998
13 years 11 months ago
Compression of Strings with Approximate Repeats
We describe a model for strings of characters that is loosely based on the Lempel Ziv model with the addition that a repeated substring can be an approximate match to the original...
Lloyd Allison, Timothy Edgoose, Trevor I. Dix
ISMB
1998
13 years 11 months ago
Sequence Assembly Validation by Multiple Restriction Digest Fragment Coverage Analysis
DNA sequence analysis depends on the accurate assembly of fragment reads for the determination of a consensus sequence. This report examines the possibility of analyzing multiple,...
Eric C. Rouchka, David J. States
AC
2004
Springer
13 years 10 months ago
Shotgun Sequence Assembly
Shotgun sequencing is the most widely used technique for determining the DNA sequence of organisms. It involves breaking up the DNA into many small pieces that can be read by auto...
Mihai Pop
GECCO
2003
Springer
14 years 3 months ago
Optimizing the Order of Taxon Addition in Phylogenetic Tree Construction Using Genetic Algorithm
Phylogenetics has gained in public favor for the analysis of DNA sequence data as molecular biology has advanced. Among a number of algorithms for phylogenetics, the fastDNAml is c...
Yong-Hyuk Kim, Seung-Kyu Lee, Byung Ro Moon