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CIBCB
2005
IEEE
14 years 1 months ago
Feedback Memetic Algorithms for Modeling Gene Regulatory Networks
— In this paper we address the problem of finding gene regulatory networks from experimental DNA microarray data. We focus on the evaluation of the performance of memetic algori...
Christian Spieth, Felix Streichert, Jochen Supper,...
CSB
2005
IEEE
166views Bioinformatics» more  CSB 2005»
14 years 1 months ago
Automated Validation of Polymerase Chain Reactions Using Amplicon Melting Curves
PCR, the polymerase chain reaction, is a fundamental tool of molecular biology. Quantitative PCR is the goldstandard methodology for determination of DNA copy numbers, quantitatin...
Tobias P. Mann, Richard Humbert, John A. Stamatoya...
CSB
2005
IEEE
205views Bioinformatics» more  CSB 2005»
14 years 1 months ago
Fractal Clustering for Microarray Data Analysis
DNA microarray experiments generate a substantial amount of information about global gene expression. Gene expression profiles can be represented as points in multi-dimensional sp...
Lu-Yong Wang, Ammaiappan Balasubramanian, Amit Cha...
CPM
2005
Springer
206views Combinatorics» more  CPM 2005»
14 years 1 months ago
A Fast Algorithm for Approximate String Matching on Gene Sequences
Abstract. Approximate string matching is a fundamental and challenging problem in computer science, for which a fast algorithm is highly demanded in many applications including tex...
Zheng Liu, Xin Chen, James Borneman, Tao Jiang
SWAT
2004
Springer
98views Algorithms» more  SWAT 2004»
14 years 1 months ago
Tight Approximability Results for Test Set Problems in Bioinformatics
In this paper, we investigate the test set problem and its variations that appear in a variety of applications. In general, we are given a universe of objects to be “distinguish...
Piotr Berman, Bhaskar DasGupta, Ming-Yang Kao