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» DNA segmentation as a model selection process
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RECOMB
2001
Springer
13 years 11 months ago
DNA segmentation as a model selection process
Previous divide-and-conquer segmentation analyses of DNA sequences do not provide a satisfactory stopping criterion for the recursion. This paper proposes that segmentation be con...
Wentian Li
BMCBI
2005
104views more  BMCBI 2005»
13 years 7 months ago
A statistical approach for array CGH data analysis
Background: Microarray-CGH experiments are used to detect and map chromosomal imbalances, by hybridizing targets of genomic DNA from a test and a reference sample to sequences imm...
Franck Picard, Stéphane Robin, Marc Laviell...
ICDM
2006
IEEE
122views Data Mining» more  ICDM 2006»
14 years 1 months ago
Optimal Segmentation Using Tree Models
Sequence data are abundant in application areas such as computational biology, environmental sciences, and telecommunications. Many real-life sequences have a strong segmental str...
Robert Gwadera, Aristides Gionis, Heikki Mannila
BMCBI
2010
125views more  BMCBI 2010»
13 years 7 months ago
Haplotype allelic classes for detecting ongoing positive selection
Background: Natural selection eliminates detrimental and favors advantageous phenotypes. This process leaves characteristic signatures in underlying genomic segments that can be r...
Julie Hussin, Philippe Nadeau, Jean-Françoi...
CSB
2003
IEEE
113views Bioinformatics» more  CSB 2003»
14 years 19 days ago
An Optimal DNA Segmentation Based on the MDL Principle
: The biological world is highly stochastic and inhomogeneous in its behaviour. There are regions in DNA with high concentration of G or C bases; stretches of sequences with an abu...
Wojciech Szpankowski, Wenhui Ren, Lukasz Szpankows...