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BMCBI
2010
202views more  BMCBI 2010»
13 years 8 months ago
NeMo: Network Module identification in Cytoscape
Background: As the size of the known human interactome grows, biologists increasingly rely on computational tools to identify patterns that represent protein complexes and pathway...
Corban G. Rivera, Rachit Vakil, Joel S. Bader
BMCBI
2010
170views more  BMCBI 2010»
13 years 8 months ago
Analysis of lifestyle and metabolic predictors of visceral obesity with Bayesian Networks
Background: The aim of this study was to provide a framework for the analysis of visceral obesity and its determinants in women, where complex inter-relationships are observed amo...
Alex Aussem, André Tchernof, Sergio Rodrigu...
BMCBI
2008
105views more  BMCBI 2008»
13 years 8 months ago
Novel computational methods for increasing PCR primer design effectiveness in directed sequencing
Background: Polymerase chain reaction (PCR) is used in directed sequencing for the discovery of novel polymorphisms. As the first step in PCR directed sequencing, effective PCR pr...
Kelvin Li, Anushka Brownley, Timothy B. Stockwell,...
BMCBI
2010
70views more  BMCBI 2010»
13 years 8 months ago
The Text-mining based PubChem Bioassay neighboring analysis
Background: In recent years, the number of High Throughput Screening (HTS) assays deposited in PubChem has grown quickly. As a result, the volume of both the structured informatio...
Lianyi Han, Tugba O. Suzek, Yanli Wang, Steve H. B...
BMCBI
2010
133views more  BMCBI 2010»
13 years 8 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang