We propose a new method to build persistent suffix trees for indexing the genomic data. Our algorithm DiGeST (Disk-Based Genomic Suffix Tree) improves significantly over previous ...
Marina Barsky, Ulrike Stege, Alex Thomo, Chris Upt...
Background: Alternative splicing is an important gene regulation mechanism. It is estimated that about 74% of multi-exon human genes have alternative splicing. High throughput tan...
Fan Mo, Xu Hong, Feng Gao, Lin Du, Jun Wang, Gilbe...
Backgorund: The completion of the Human Genome Project has resulted in large quantities of biological data which are proving difficult to manage and integrate effectively. There i...
Paolo Romano 0001, Domenico Marra, Luciano Milanes...
Background -: Sequencing of EST and BAC end datasets is no longer limited to large research groups. Drops in per-base pricing have made high throughput sequencing accessible to in...
Stephen E. Diener, Thomas D. Houfek, Sam E. Kalat,...
The development of high throughput techniques and large-scale studies in the biological sciences has given rise to an explosive growth in both the volume and types of data availab...
Shuo Liu, Steve Lin, Mark Woon, Teri E. Klein, Rus...