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BMCBI
2008
124views more  BMCBI 2008»
13 years 9 months ago
A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
Huanying Ge, Chao Cheng, Lei M. Li
BMCBI
2008
143views more  BMCBI 2008»
13 years 9 months ago
Automatic detection of exonic splicing enhancers (ESEs) using SVMs
Background: Exonic splicing enhancers (ESEs) activate nearby splice sites and promote the inclusion (vs. exclusion) of exons in which they reside, while being a binding site for S...
Britta Mersch, Alexander Gepperth, Sándor S...
BMCBI
2008
138views more  BMCBI 2008»
13 years 9 months ago
Comparative analyses of bidirectional promoters in vertebrates
Background: Orthologous genes with deep phylogenetic histories are likely to retain similar regulatory features. In this report we utilize orthology assignments for pairs of genes...
Mary Qu Yang, James Taylor, Laura Elnitski
BMCBI
2008
90views more  BMCBI 2008»
13 years 9 months ago
Ortholog-based protein-protein interaction prediction and its application to inter-species interactions
Background: The rapid growth of protein-protein interaction (PPI) data has led to the emergence of PPI network analysis. Despite advances in high-throughput techniques, the intera...
Sheng-An Lee, Chen-hsiung Chan, Chi-Hung Tsai, Jin...
BMCBI
2008
133views more  BMCBI 2008»
13 years 9 months ago
Towards ontology-driven navigation of the lipid bibliosphere
Background: The indexing of scientific literature and content is a relevant and contemporary requirement within life science information systems. Navigating information available ...
Christopher J. O. Baker, Kanagasabai Rajaraman, We...
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