Background: Sequencing metagenomes that were pre-amplified with primer-based methods requires the removal of the additional tag sequences from the datasets. The sequenced reads ca...
Robert Schmieder, Yan Wei Lim, Forest Rohwer, Robe...
Understanding the functional significance of alternative splicing and other mechanisms that generate RNA transcript diversity is an important challenge facing modern-day molecular...
Ann E. Loraine, Gregg A. Helt, Melissa S. Cline, M...
Background: Identifying cis-regulatory elements is crucial to understanding gene expression, which highlights the importance of the computational detection of overrepresented tran...
Background: Mitochondria are sub-cellular organelles that have a central role in energy production and in other metabolic pathways of all eukaryotic respiring cells. In the last f...
Domenico Catalano, Flavio Licciulli, Antonio Turi,...
Information about small genetic variations in organisms, known as single nucleotide polymorphism (SNPs), is crucial to identify candidate genes that have a role in disease suscepti...
Paolo Missier, Suzanne M. Embury, Cornelia Hedeler...