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142
Voted
BMCBI
2006
15 years 3 months ago
2006
Background: When accurate models for the divergent evolution of protein sequences are integrated with complementary biological information, such as folded protein structures, anal...
133
Voted
BMCBI
2006
15 years 3 months ago
2006
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
127
Voted
CJ
2006
15 years 3 months ago
2006
s the development of an abstract description of what there is in the world in an application-independent form. This paper argues that attempts to support information systems intero...
126
Voted
BMCBI
2005
15 years 3 months ago
2005
Background: Public databases now contain multitude of complete bacterial genomes, including several genomes of the same species. The available data offers new opportunities to add...
131
Voted
BMCBI
2005
15 years 3 months ago
2005
Background: Type 1 diabetes mellitus (T1DM) is a autoimmune disease caused by a long-term negative balance between immune-mediated beta-cell damage and beta-cell repair/regenerati...