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BMCBI
2004
208views more  BMCBI 2004»
13 years 7 months ago
Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
Background: Hidden Markov Models (HMMs) have proven very useful in computational biology for such applications as sequence pattern matching, gene-finding, and structure prediction...
Vadim Alexandrov, Mark Gerstein
SIGMOD
2008
ACM
164views Database» more  SIGMOD 2008»
14 years 7 months ago
Finding frequent items in probabilistic data
Computing statistical information on probabilistic data has attracted a lot of attention recently, as the data generated from a wide range of data sources are inherently fuzzy or ...
Qin Zhang, Feifei Li, Ke Yi
DNIS
2005
Springer
112views Database» more  DNIS 2005»
14 years 1 months ago
Modelling Peer-to-Peer Data Networks Under Complex System Theory
: A Peer-to-peer Data Network (PDN) is an open and evolving society of peer nodes that assemble into a network to share their data for mutual benefit. PDNs are enabled by distribu...
Cyrus Shahabi, Farnoush Banaei Kashani
BMCBI
2010
136views more  BMCBI 2010»
13 years 7 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
FCCM
2011
IEEE
311views VLSI» more  FCCM 2011»
12 years 11 months ago
String Matching in Hardware Using the FM-Index
—String matching is a ubiquitous problem that arises in a wide range of applications in computing, e.g., packet routing, intrusion detection, web querying, and genome analysis. D...
Edward Fernandez, Walid Najjar, Stefano Lonardi