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» Data-adaptive test statistics for microarray data
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BMCBI
2010
125views more  BMCBI 2010»
13 years 7 months ago
Asymmetric microarray data produces gene lists highly predictive of research literature on multiple cancer types
Background: Much of the public access cancer microarray data is asymmetric, belonging to datasets containing no samples from normal tissue. Asymmetric data cannot be used in stand...
Noor B. Dawany, Aydin Tozeren
JMLR
2010
94views more  JMLR 2010»
13 years 5 months ago
A Rotation Test to Verify Latent Structure
We consider here how to tell whether a latent variable that has been estimated in a multivariate regression context might be real. Often a followup investigation will find a real...
Patrick O. Perry, Art B. Owen
BMCBI
2006
116views more  BMCBI 2006»
13 years 7 months ago
Integrative missing value estimation for microarray data
Background: Missing value estimation is an important preprocessing step in microarray analysis. Although several methods have been developed to solve this problem, their performan...
Jianjun Hu, Haifeng Li, Michael S. Waterman, Xiang...
BMCBI
2010
85views more  BMCBI 2010»
13 years 7 months ago
Robust test method for time-course microarray experiments
Background: In a time-course microarray experiment, the expression level for each gene is observed across a number of time-points in order to characterize the temporal trajectorie...
Insuk Sohn, Kouros Owzar, Stephen L. George, Sujon...
BMCBI
2006
147views more  BMCBI 2006»
13 years 7 months ago
Grouping Gene Ontology terms to improve the assessment of gene set enrichment in microarray data
Background: Gene Ontology (GO) terms are often used to assess the results of microarray experiments. The most common way to do this is to perform Fisher's exact tests to find...
Alex Lewin, Ian C. Grieve