PRINTS is a database of protein family ‘fingerprints’ offering a diagnostic resource for newly-determined sequences. By contrast with PROSITE, which uses single consensus expr...
Terri K. Attwood, Michael E. Beck, Darren R. Flowe...
Background: The process of horizontal gene transfer (HGT) is believed to be widespread in Bacteria and Archaea, but little comparative data is available addressing its occurrence ...
We present an index structure for managing weightedsequences in large databases. A weighted-sequence is defined as a two-dimensional structure where each element in the sequence i...
Multiple sequence alignments are essential in computational sequence and structural analysis, with applications in homology detection, structure modeling, function prediction and ...
Background: Analysis of complex samples with tandem mass spectrometry (MS/MS) has become routine in proteomic research. However, validation of database search results creates a bo...