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BMCBI
2005
133views more  BMCBI 2005»
13 years 7 months ago
Systematic determination of the mosaic structure of bacterial genomes: species backbone versus strain-specific loops
Background: Public databases now contain multitude of complete bacterial genomes, including several genomes of the same species. The available data offers new opportunities to add...
Hélène Chiapello, I. Bourgait, F. So...
BMCBI
2005
94views more  BMCBI 2005»
13 years 7 months ago
Computational identification of strain-, species- and genus-specific proteins
Background: The identification of unique proteins at different taxonomic levels has both scientific and practical value. Strain-, species- and genus-specific proteins can provide ...
Raja Mazumder, Darren A. Natale, Sudhir Murthy, Ra...
BMCBI
2004
154views more  BMCBI 2004»
13 years 7 months ago
Base-By-Base: Single nucleotide-level analysis of whole viral genome alignments
Background: With ever increasing numbers of closely related virus genomes being sequenced, it has become desirable to be able to compare two genomes at a level more detailed than ...
Ryan Brodie, Alex J. Smith, Rachel L. Roper, Vasil...
BMCBI
2004
114views more  BMCBI 2004»
13 years 7 months ago
Profiled support vector machines for antisense oligonucleotide efficacy prediction
Background: This paper presents the use of Support Vector Machines (SVMs) for prediction and analysis of antisense oligonucleotide (AO) efficacy. The collected database comprises ...
Gustavo Camps-Valls, Alistair M. Chalk, Antonio J....
BMCBI
2004
149views more  BMCBI 2004»
13 years 7 months ago
MiCoViTo: a tool for gene-centric comparison and visualization of yeast transcriptome states
Background: Information obtained by DNA microarray technology gives a rough snapshot of the transcriptome state, i.e., the expression level of all the genes expressed in a cell po...
Gaëlle Lelandais, Philippe Marc, Pierre Vince...