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BMCBI
2006
85views more  BMCBI 2006»
13 years 8 months ago
Searching for interpretable rules for disease mutations: a simulated annealing bump hunting strategy
Background: Understanding how amino acid substitutions affect protein functions is critical for the study of proteins and their implications in diseases. Although methods have bee...
Rui Jiang, Hua Yang, Fengzhu Sun, Ting Chen
IJCNN
2006
IEEE
14 years 1 months ago
A Columnar Competitive Model with Simulated Annealing for Solving Combinatorial Optimization Problems
— One of the major drawbacks of the Hopfield network is that when it is applied to certain polytopes of combinatorial problems, such as the traveling salesman problem (TSP), the...
Eu Jin Teoh, Huajin Tang, Kay Chen Tan
FOCS
2007
IEEE
14 years 2 months ago
Adaptive Simulated Annealing: A Near-optimal Connection between Sampling and Counting
We present a near-optimal reduction from approximately counting the cardinality of a discrete set to approximately sampling elements of the set. An important application of our wo...
Daniel Stefankovic, Santosh Vempala, Eric Vigoda