Background: Members of a protein family often have highly conserved sequences; most of these sequences carry identical biological functions and possess similar three-dimensional (...
With the exponential growth of biological sequence databases, it has become critical to develop effective techniques for storing, querying, and analyzing these massive data. Suffi...
Background: The Smith-Waterman algorithm for local sequence alignment is more sensitive than heuristic methods for database searching, but also more time-consuming. The fastest ap...
Time-oriented progress estimation for parallel queries is a challenging problem that has received only limited attention. In this paper, we present ParaTimer, a new type of timere...
Sequence homologs are an important source of information about proteins. Amino acid profiles, representing the position-specific mutation probabilities found in profiles, are a ri...
Sean O'Rourke, Gal Chechik, Robin Friedman, Eleaza...