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» Decomposing Gene Expression into Cellular Processes
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BMCBI
2010
108views more  BMCBI 2010»
13 years 10 months ago
Error, reproducibility and sensitivity : a pipeline for data processing of Agilent oligonucleotide expression arrays
Background: Expression microarrays are increasingly used to obtain large scale transcriptomic information on a wide range of biological samples. Nevertheless, there is still much ...
Benjamin Chain, Helen Bowen, John Hammond, Wilfrie...
BMCBI
2006
138views more  BMCBI 2006»
13 years 10 months ago
Determination of strongly overlapping signaling activity from microarray data
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Ghislain Bidaut, Karsten Suhre, Jean-Michel Claver...
NAR
2008
174views more  NAR 2008»
13 years 8 months ago
miRGator: an integrated system for functional annotation of microRNAs
MicroRNAs (miRNAs) constitute an important class of regulators that are involved in various cellular and disease processes. However, the functional significance of each miRNA is m...
Seungyoon Nam, Bumjin Kim, Seokmin Shin, Sanghyuk ...
BMCBI
2010
164views more  BMCBI 2010»
13 years 10 months ago
Gene regulatory networks modelling using a dynamic evolutionary hybrid
Background: Inference of gene regulatory networks is a key goal in the quest for understanding fundamental cellular processes and revealing underlying relations among genes. With ...
Ioannis A. Maraziotis, Andrei Dragomir, Dimitris T...
BMCBI
2006
82views more  BMCBI 2006»
13 years 10 months ago
A method for computing the overall statistical significance of a treatment effect among a group of genes
Background: In studies that use DNA arrays to assess changes in gene expression, our goal is to evaluate the statistical significance of treatments on sets of genes. Genes can be ...
Robert R. Delongchamp, Taewon Lee, Cruz Velasco