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» Defining functional distances over Gene Ontology
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BMCBI
2005
159views more  BMCBI 2005»
13 years 8 months ago
Columba: an integrated database of proteins, structures, and annotations
Background: Structural and functional research often requires the computation of sets of protein structures based on certain properties of the proteins, such as sequence features,...
Silke Trißl, Kristian Rother, Heiko Mül...
BMCBI
2006
167views more  BMCBI 2006»
13 years 8 months ago
GOurmet: A tool for quantitative comparison and visualization of gene expression profiles based on gene ontology (GO) distributi
Background: The ever-expanding population of gene expression profiles (EPs) from specified cells and tissues under a variety of experimental conditions is an important but difficu...
Jason M. Doherty, Lynn K. Carmichael, Jason C. Mil...
BMCBI
2008
127views more  BMCBI 2008»
13 years 8 months ago
MetaMine - A tool to detect and analyse gene patterns in their environmental context
Background: Modern sequencing technologies allow rapid sequencing and bioinformatic analysis of genomes and metagenomes. With every new sequencing project a vast number of new pro...
Uta Bohnebeck, Thierry Lombardot, Renzo Kottmann, ...
JBCB
2010
138views more  JBCB 2010»
13 years 3 months ago
Hierarchical Classification of Gene Ontology Terms Using the Gostruct Method
Protein function prediction is an active area of research in bioinformatics. And yet, transfer of annotation on the basis of sequence or structural similarity remains widely used ...
Artem Sokolov, Asa Ben-Hur
BMCBI
2005
112views more  BMCBI 2005»
13 years 8 months ago
Integration of the Gene Ontology into an object-oriented architecture
Background: To standardize gene product descriptions, a formal vocabulary defined as the Gene Ontology (GO) has been developed. GO terms have been categorized into biological proc...
Daniel Shegogue, W. Jim Zheng