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BMCBI
2010
112views more  BMCBI 2010»
13 years 8 months ago
Orientation-dependent backbone-only residue pair scoring functions for fixed backbone protein design
Background: Empirical scoring functions have proven useful in protein structure modeling. Most such scoring functions depend on protein side chain conformations. However, backbone...
Andrew J. Bordner
KDD
2009
ACM
232views Data Mining» more  KDD 2009»
14 years 9 months ago
Classification of software behaviors for failure detection: a discriminative pattern mining approach
Software is a ubiquitous component of our daily life. We often depend on the correct working of software systems. Due to the difficulty and complexity of software systems, bugs an...
David Lo, Hong Cheng, Jiawei Han, Siau-Cheng Khoo,...
VLDB
1998
ACM
101views Database» more  VLDB 1998»
14 years 20 days ago
On Optimal Node Splitting for R-trees
The problem of finding an optimal bipartition of a rectangle set has a direct impact on query performance of dynamic R-trees. During update operations, overflowed nodes need to be...
Yván J. García, Mario A. Lopez, Scot...
BMCBI
2010
126views more  BMCBI 2010»
13 years 5 months ago
Systematic integration of experimental data and models in systems biology
Background: The behaviour of biological systems can be deduced from their mathematical models. However, multiple sources of data in diverse forms are required in the construction ...
Peter Li, Joseph O. Dada, Daniel Jameson, Irena Sp...
CLUSTER
2009
IEEE
14 years 3 months ago
Analyzing massive astrophysical datasets: Can Pig/Hadoop or a relational DBMS help?
Abstract— As the datasets used to fuel modern scientific discovery grow increasingly large, they become increasingly difficult to manage using conventional software. Parallel d...
Sarah Loebman, Dylan Nunley, YongChul Kwon, Bill H...