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FOCS
2006
IEEE
14 years 2 months ago
Algorithms on negatively curved spaces
d abstract] Robert Krauthgamer ∗ IBM Almaden James R. Lee † Institute for Advanced Study We initiate the study of approximate algorithms on negatively curved spaces. These spa...
Robert Krauthgamer, James R. Lee
BMCBI
2010
116views more  BMCBI 2010»
13 years 8 months ago
Optimization algorithms for functional deimmunization of therapeutic proteins
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
Andrew S. Parker, Wei Zheng, Karl E. Griswold, Chr...
CORR
2010
Springer
249views Education» more  CORR 2010»
13 years 8 months ago
Lower Bounds on Near Neighbor Search via Metric Expansion
In this paper we show how the complexity of performing nearest neighbor (NNS) search on a metric space is related to the expansion of the metric space. Given a metric space we loo...
Rina Panigrahy, Kunal Talwar, Udi Wieder
LSSC
2007
Springer
14 years 2 months ago
Bridging Methods for Coupling Atomistic and Continuum Models
Abstract. We review some recent developments in the coupling of atomistic and continuum models based on the blending of the two models in a bridge region connecting the other two r...
Santiago Badia, Pavel B. Bochev, Max Gunzburger, R...
MP
2010
126views more  MP 2010»
13 years 6 months ago
Two row mixed-integer cuts via lifting
Recently, Andersen et al. [1], Borozan and Cornu´ejols [7] and Cornu´ejols and Margot [10] characterized extreme inequalities of a system of two rows with two free integer varia...
Santanu S. Dey, Laurence A. Wolsey