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BMCBI
2006
153views more  BMCBI 2006»
13 years 7 months ago
The 3of5 web application for complex and comprehensive pattern matching in protein sequences
Background: The identification of patterns in biological sequences is a key challenge in genome analysis and in proteomics. Frequently such patterns are complex and highly variabl...
Markus Seiler, Alexander Mehrle, Annemarie Poustka...
BMCBI
2006
108views more  BMCBI 2006»
13 years 7 months ago
A new pooling strategy for high-throughput screening: the Shifted Transversal Design
Background: In binary high-throughput screening projects where the goal is the identification of low-frequency events, beyond the obvious issue of efficiency, false positives and ...
Nicolas Thierry-Mieg
BMCBI
2006
97views more  BMCBI 2006»
13 years 7 months ago
REEF: searching REgionally Enriched Features in genomes
Background: In Eukaryotic genomes, different features including genes are not uniformly distributed. The integration of annotation information and genomic position of functional D...
Alessandro Coppe, Gian Antonio Danieli, Stefania B...
BMCBI
2006
86views more  BMCBI 2006»
13 years 7 months ago
Identification of QTLs controlling gene expression networks defined a priori
Background: Gene expression microarrays allow the quantification of transcript accumulation for many or all genes in a genome. This technology has been utilized for a range of inv...
Daniel J. Kliebenstein, Marilyn A. L. West, Hans v...
BMCBI
2006
128views more  BMCBI 2006»
13 years 7 months ago
Model-driven user interfaces for bioinformatics data resources: regenerating the wheel as an alternative to reinventing it
Background: The proliferation of data repositories in bioinformatics has resulted in the development of numerous interfaces that allow scientists to browse, search and analyse the...
Kevin L. Garwood, Christopher Garwood, Cornelia He...