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» Design: One, but in different forms
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BMCBI
2010
104views more  BMCBI 2010»
13 years 7 months ago
Bidirectional best hit r-window gene clusters
Background: Conserved gene clusters are groups of genes that are located close to one another in the genomes of several species. They tend to code for proteins that have a functio...
Melvin Zhang, Hon Wai Leong
BMCBI
2008
98views more  BMCBI 2008»
13 years 7 months ago
Empirical Bayes models for multiple probe type microarrays at the probe level
Background: When analyzing microarray data a primary objective is often to find differentially expressed genes. With empirical Bayes and penalized t-tests the sample variances are...
Magnus Åstrand, Petter Mostad, Mats Rudemo
BMCBI
2010
110views more  BMCBI 2010»
13 years 7 months ago
MultiRTA: A simple yet reliable method for predicting peptide binding affinities for multiple class II MHC allotypes
Background: The binding of peptide fragments of antigens to class II MHC is a crucial step in initiating a helper T cell immune response. The identification of such peptide epitop...
Andrew J. Bordner, Hans D. Mittelmann
BMCBI
2007
174views more  BMCBI 2007»
13 years 7 months ago
Normalization method for metabolomics data using optimal selection of multiple internal standards
Background: Success of metabolomics as the phenotyping platform largely depends on its ability to detect various sources of biological variability. Removal of platform-specific so...
Marko Sysi-Aho, Mikko Katajamaa, Laxman Yetukuri, ...
BMCBI
2008
108views more  BMCBI 2008»
13 years 7 months ago
SPRINT: A new parallel framework for R
Background: Microarray analysis allows the simultaneous measurement of thousands to millions of genes or sequences across tens to thousands of different samples. The analysis of t...
Jon Hill, Matthew Hambley, Thorsten Forster, Murie...