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BMCBI
2006
153views more  BMCBI 2006»
13 years 10 months ago
Discovery of time-delayed gene regulatory networks based on temporal gene expression profiling
Background: It is one of the ultimate goals for modern biological research to fully elucidate the intricate interplays and the regulations of the molecular determinants that prope...
Xia Li, Shaoqi Rao, Wei Jiang, Chuanxing Li, Yun X...
BMCBI
2006
182views more  BMCBI 2006»
13 years 10 months ago
A database and tool, IM Browser, for exploring and integrating emerging gene and protein interaction data for Drosophila
Background: Biological processes are mediated by networks of interacting genes and proteins. Efforts to map and understand these networks are resulting in the proliferation of int...
Svetlana Pacifico, Guozhen Liu, Stephen Guest, Jod...
BMCBI
2006
87views more  BMCBI 2006»
13 years 10 months ago
Prediction of indirect interactions in proteins
Background: Both direct and indirect interactions determine molecular recognition of ligands by proteins. Indirect interactions can be defined as effects on recognition controlled...
Peteris Prusis, Staffan Uhlén, Ramona Petro...
BMCBI
2006
152views more  BMCBI 2006»
13 years 10 months ago
A two-stage approach for improved prediction of residue contact maps
Background: Protein topology representations such as residue contact maps are an important intermediate step towards ab initio prediction of protein structure. Although improvemen...
Alessandro Vullo, Ian Walsh, Gianluca Pollastri
BMCBI
2006
86views more  BMCBI 2006»
13 years 10 months ago
The impact of sample imbalance on identifying differentially expressed genes
Background: Recently several statistical methods have been proposed to identify genes with differential expression between two conditions. However, very few studies consider the p...
Kun Yang, Jianzhong Li, Hong Gao
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