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BMCBI
2005
108views more  BMCBI 2005»
13 years 10 months ago
SplitTester: software to identify domains responsible for functional divergence in protein family
Background: Many protein families have undergone functional divergence after gene duplications such that current subgroups of the family carry out overlapping but distinct biologi...
Xiang Gao, Kent Vander Velden, Daniel F. Voytas, X...
BMCBI
2005
117views more  BMCBI 2005»
13 years 10 months ago
An SVM-based system for predicting protein subnuclear localizations
Background: The large gap between the number of protein sequences in databases and the number of functionally characterized proteins calls for the development of a fast computatio...
Zhengdeng Lei, Yang Dai
BMCBI
2005
116views more  BMCBI 2005»
13 years 10 months ago
Can Zipf's law be adapted to normalize microarrays?
Background: Normalization is the process of removing non-biological sources of variation between array experiments. Recent investigations of data in gene expression databases for ...
Timothy Lu, Christine M. Costello, Peter J. P. Cro...
BMCBI
2005
180views more  BMCBI 2005»
13 years 10 months ago
arrayCGHbase: an analysis platform for comparative genomic hybridization microarrays
Background: The availability of the human genome sequence as well as the large number of physically accessible oligonucleotides, cDNA, and BAC clones across the entire genome has ...
Björn Menten, Filip Pattyn, Katleen De Preter...
BMCBI
2005
132views more  BMCBI 2005»
13 years 10 months ago
CLPM: A Cross-Linked Peptide Mapping Algorithm for Mass Spectrometric Analysis
Background: Protein-protein, protein-DNA and protein-RNA interactions are of central importance in biological systems. Quadrapole Time-of-flight (Q-TOF) mass spectrometry is a sen...
Yong Tang, Yingfeng Chen, Cheryl F. Lichti, Roger ...
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