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» Design methods as discourse on practice
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BMCBI
2010
105views more  BMCBI 2010»
13 years 7 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
BMCBI
2010
98views more  BMCBI 2010»
13 years 7 months ago
Learning to predict expression efficacy of vectors in recombinant protein production
Background: Recombinant protein production is a useful biotechnology to produce a large quantity of highly soluble proteins. Currently, the most widely used production system is t...
Wen-Ching Chan, Po-Huang Liang, Yan-Ping Shih, Uen...
CE
2008
102views more  CE 2008»
13 years 7 months ago
E-Science in the classroom - Towards viability
E-Science has the potential to transform school science by enabling learners, teachers and research scientists to engage together in authentic scientific enquiry, collaboration an...
Joshua Underwood, Hilary Smith, Rosemary Luckin, G...
CGA
2008
13 years 7 months ago
Mobile 3D City Maps
ion and abstraction. By the end of the 20th century, technology had advanced to the point where computerized methods had revolutionized surveying and mapmaking practices. Now, the ...
Antti Nurminen
BMCBI
2006
131views more  BMCBI 2006»
13 years 7 months ago
Statistical modeling of biomedical corpora: mining the Caenorhabditis Genetic Center Bibliography for genes related to life span
Background: The statistical modeling of biomedical corpora could yield integrated, coarse-to-fine views of biological phenomena that complement discoveries made from analysis of m...
David M. Blei, K. Franks, Michael I. Jordan, I. Sa...