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BMCBI
2006
89views more  BMCBI 2006»
13 years 8 months ago
A joint model for nonparametric functional mapping of longitudinal trajectory and time-to-event
Background: The characterization of the relationship between a longitudinal response process and a time-to-event has been a pressing challenge in biostatistical research. This has...
Min Lin, Rongling Wu
BMCBI
2006
87views more  BMCBI 2006»
13 years 8 months ago
Prediction of indirect interactions in proteins
Background: Both direct and indirect interactions determine molecular recognition of ligands by proteins. Indirect interactions can be defined as effects on recognition controlled...
Peteris Prusis, Staffan Uhlén, Ramona Petro...
BMCBI
2006
249views more  BMCBI 2006»
13 years 8 months ago
Gene functional similarity search tool (GFSST)
Background: With the completion of the genome sequences of human, mouse, and other species and the advent of high throughput functional genomic research technologies such as biomi...
Peisen Zhang, Jinghui Zhang, Huitao Sheng, James J...
BMCBI
2006
86views more  BMCBI 2006»
13 years 8 months ago
The impact of sample imbalance on identifying differentially expressed genes
Background: Recently several statistical methods have been proposed to identify genes with differential expression between two conditions. However, very few studies consider the p...
Kun Yang, Jianzhong Li, Hong Gao
BMCBI
2006
103views more  BMCBI 2006»
13 years 8 months ago
Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression
Background: The identification of differentially expressed genes (DEGs) from Affymetrix GeneChips arrays is currently done by first computing expression levels from the low-level ...
Sébastien Lemieux
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